Ensaios Clínicos em Fase de Recrutamento

Atualmente, estão em fase de recrutamento para realização no Hospital da Luz os seguintes ensaios clinicos:

  • Ensaios clínicos na área do carcinoma da mama

    •  Ensaio clínico OLYMPIA

    A randomised, double-blind, parallel group, placebo-controlled multi-centre Phase III study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy.

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2013-003839-30/PT

    • Ensaio clínico PALLAS:

    A randomized phase III trial of Palbociclib with standard adjuvant endocrine therapy versus standard adjuvant endocrine therapy alone for hormone receptor positive (HR+) / human epidermal growth factor receptor 2 (HER2)-negative early breast cancer

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2014-005181-30/PT

     

     

     

     

  • Ensaios clínicos na área do carcinoma da próstata

    • Ensaio clínico ARAMIS

    A multinational, randomized, double-blind, placebo-controlled, phase III efficacy and safety study of ODM-201 in men with high-risk non-metastatic castration-resistant prostate cancer

    Para mais informações:
    https://clinicaltrials.gov/ct2/show/NCT02200614?term=ARAMIS&rank=2

  • Ensaios clínicos na área do carcinoma do estômago

    • Ensaio clinico TAS-102-302

    Randomized, Double-Blind, Phase 3 Study Evaluating TAS-102 plus Best Supportive Care (BSC) versus Placebo plus BSC in Patients with Metastatic Gastric Cancer Refractory to Standard Treatments.

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-002683-16/PT

     

  • Ensaios clínicos na área da diabetes

    • Ensaio clínico FIDELIO

    A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone, in addition to standard of care, on the progression of kidney disease in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease

    Para mais informações: https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-000990-11/PT

    • Ensaio clínico FIGARO

    A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone on the reduction of cardiovascular morbidity and mortality in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease in addition to standard of care

    Para mais informações: https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-000950-39/PT

  • Ensaios clínicos na área da doença de Crohn

    • Ensaio clínico REVOLVE

    “A Phase 3, randomized, double-blind, placebo-controlled, multicenter study to investigate the efficacy and safety of mongersen (GED-0301) for the treatment of subjects with active Crohn’s disease.”

    Para mais informações:

    https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-001925-18/PT

  • Ensaios clínicos na área da esclerose múltipla

    • Ensaio Clínico COMB157G2302

    A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis.

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-005419-33/PT

    • Ensaio Clínico PLENO

    Open-label, Randomized, 2-arm, Active Comparator Study to Evaluate Safety and Tolerability in Portuguese Patients with Relapsing Remitting Multiple Sclerosis (MS) Transitioning from Current Subcutaneous Interferon Therapy to Peginterferon Beta 1a (PLEGRIDY™)

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2016-000434-21/PT

  • Ensaios clínicos na área da insuficiência cardíaca

    • Ensaio clínico TRANSITION

    “A multicenter, randomized, open label, parallel group study comparing pre-discharge and post-discharge treatment initiation with LCZ696 in heart failure patients with reduced ejectIon-fraction hospitalized for an acute decompensation event (ADHF)”

    Para mais informações: https://www.clinicaltrialsregister.eu/ctr-search/trial/2015-003266-87/PT

    • Ensaio Clínico GALACTIC-HF

    A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects With Chronic Heart Failure With Reduced Ejection Fraction

    Mais informações em: https://www.clinicaltrialsregister.eu/ctr-search/trial/2016-002299-28/PT

    • Ensaio clínico PANACHE

    “A multicenter, randomized, placebo-controlled, parallel group, double blind, dose-finding Phase II trial to study the efficacy, safety, pharmacokinetic and pharmacodynamic effects of the oral partial adenosine A1 receptor agonist neladenoson bialanate over 20 weeks in patients with chronic heart failure and preserved ejection fraction”

    Para mais informações: https://www.clinicaltrialsregister.eu/ctr-search/trial/2016-004062-26/PT

     

  • Ensaios clínicos na área do tromboembolismo pulmonar

    • Ensaio clínico Hot PE

    “Home treatment of patients with low-risk pulmonary embolism with the oral factor xa inhibitor rivaroxaban: prospective management trial”

    Para mais informações:
    https://www.clinicaltrialsregister.eu/ctr-search/trial/2013-001657-28/PT

     

Se estiver interessado em saber mais sobre algum dos ensaios clínicos referidos, poderá enviar um e-mail para ensaiosclinicos.lisboa@hospitaldaluz.pt e a equipa do Centro de Investigação Clínica do Hospital da Luz entrará em contacto consigo.

O envio deste e-mail não é garantia da participação num ensaio clínico.