16 May 2019 Bilirubin is a pigment that results from the breakdown of red blood cells (carrying oxygen) and is metabolised in the liver. While in the uterus , a foetus may produce more red blood cells than it will need after birth. After birth , the baby’s body destroys these surplus red blood cells and, as bilirubin is among their constituents, it is released into the bloodstream. Origin of jaundice in newborns If the concentration of bilirubin exceeds the liver’s capacity to metabolise it, the blood level increases. Above certain levels it results in the yellowing of the baby’s skin and eyes. Jaundice in newborns: Usually appears during the first week of life; Occurs in about 60% of term babies; Is even more common in premature babies. If jaundice persists beyond the first 10 days of life or reappears, there is usually a reason requiring further investigation . Treatment of jaundice in newborns When very high bilirubin levels are suspected in a newborn with jaundice, its blood levels can be measured and there may be a need for inpatient phototherapy treatment. The fluorescent light from phototherapy facilitates the conversion of bilirubin into a less aggressive substance that is easier for the body to eliminate. The length of treatment varies and also depends on other factors, such as: Diet; The baby's evacuation pattern. After discharge, it may be necessary to monitor the baby , especially if bilirubin levels were very high. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.