20 May 2019 Positron emission tomography with computed tomography (PET-CT) is a nuclear medicine diagnostic technique that produces functional images with anatomical references. It differs from other nuclear medicine diagnosis methods because of use of positron-emitting radiopharmaceuticals, which mark molecules in physiological processes. It shows their distribution in the body and gives a precise anatomical reference. To perform 18F-Fluoride PET-CT, a fluoride derivative, sodium fluoride, labelled with a radioactive product, is injected intravenously into a vein in the forearm. Administration of this radiopharmaceutical is safe and no significant adverse reactions are known. The patient then spends 30 to 60 minutes at rest, with oral or intravenous hydration. The imaging takes between 15 and 30 minutes. PET-CT with this radiopharmaceutical has better results to bone scintigraphy and other examinations that evaluate the skeleton and bone segments and also helps assess bone marrow changes. This radiopharmaceutical has been used for about a decade in the United States and some European countries. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. . The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.
