15 May 2019 Toxic erythema of the newborn involves reddish spots , with 1 to 2 cm in diameter, all over the baby’s body. These spots: May be rough in appearance ; Sometimes have a paler, vesicular centre. They appear anywhere on the body, except for the palms of the hands and soles of the feet, and disappear spontaneously. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.