9 May 2019 Prostaglandins are substances normally produced by the body and are involved in a number of physiological functions , such as: Protection of the stomach lining Regulation of blood pressure Pain Inflammation. When NSAIDs block the synthesis of prostaglandins, they therefore: Relieve pain and inflammation Interfere with their protective functions. For this reason, their possible side effects are: Gastric disorders Gastrointestinal bleeding. The risk of problems increases with prolonged use of NSAIDs. These products should be used with caution in patients who: Have gastric ulcers Are taking vitamin K antagonist anticoagulants. Acetylsalicylic acid and ibuprofen are non-steroidal anti-inflammatory drugs. Children and adolescents should not be given acetylsalicylic acid. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.
