20 May 2019 The thyroid is shaped like a butterfly. It has a right and left lobe connected by a bridge (the isthmus). It is an endocrine gland, which produces hormones with important functions in the body: Thyroxine (T4) and triiodothyronine (T3) control the way the body uses energy. They help regulate the metabolism and body growth, development and temperature. Calcitonin is involved in calcium metabolism. Thyroid hormone production is regulated by the thyroid stimulating hormone or thyrotropin (TSH) produced by the pituitary gland (the endocrine gland in the brain). In turn, TSH production is stimulated by the thyrotropin-releasing hormone (TRH) produced by the hypothalamus. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.