9 May 2019 Lower genital tract biopsies consist of removing a small amount of tissue from the vulva, vagina or cervix for testing. Biopsies of the lower genital tract do not usually require anaesthesia . However, a local anaesthetic is used when warranted. The tissue sample removed in the biopsy is submitted for an anatomical pathology examination for a final diagnosis. Biopsies of the lower genital tract are safe . However, despite their low incidence, some complications are possible . They include: Bleeding (immediate or later); Infection; Accidental burn in electrosurgery; Vagal reaction with lipotomy; Allergic reaction to the local anaesthetic. This article was written with the support of physicians and other clinical professionals from the Hospital da Luz network. The content published in the Health Guide is intended for the general public and is provided for informational and educational purposes only. It does not replace individual medical assessment, diagnosis, or personalized clinical advice from a qualified healthcare professional. The content is produced or reviewed by physicians and other healthcare professionals at Hospital da Luz and is based on the knowledge available at the time of publication or the most recent update, as indicated at the beginning of each item.